Generic Name: ciclopirox topical (sye kloe PEER ox) Brand Names: (Loprox cream, Spanish name) What is Ciclopirox cream? Ciclopirox is a broad-spectrum, antifungal agent that inhibits the growth of pathogenic dermatophytes, yeasts, and Malassezia furfur. Ciclopirox exhibits fungicidal activity in vitro against isolates of Trichophyton rubrum, Trichophyton mentagrophytes, Epidermophyton floccosum, Microsporum canis, and Candida albicans.. Please consult your physician before taking this medication.