Brand name: Glucophage Generic name: Metformin hydrochloride Why is Glucophage prescribed? Glucophage is an oral antidiabetic medication used to treat type 2 (non-insulin-dependent) diabetes. Diabetes develops when the body proves unable to burn sugar and the unused sugar builds up in the bloodstream. Glucophage lowers the amount of sugar in your blood by decreasing sugar production and absorption and helping your body respond better to its own insulin, which promotes the burning of sugar. It does not, however, increase the body's production of insulin. Glucophage is sometimes prescribed along with insulin or certain other oral antidiabetic drugs such as glyburide or glipizide. It is also used alone. Standard Glucophage tablets are taken two or three times daily. An extended-release form (Glucophage XR) is available for once-daily dosing. Always remember that Glucophage is an aid to, not a substitute for, good diet and exercise Failure to follow a sound diet and exercise plan can lead to serious complications such as dangerously high or low blood sugar levels. Remember, too, that Glucophage is not an oral form of insulin and cannot be used in place of insulin. Metformin may also be used for purposes other than those listed in this medication guide. Please consult your physician before taking any medication.