Generic name: Estradiol Brand names: EstroGel, (Spanish name, Oestrogel) Why is EstroGel prescribed? EstroGel is used to ease some symptoms of menopause, such as moderate to severe hot flashes (feelings of warmth in the face, neck, and chest, or sudden strong feelings of heat and sweating) and burning and itching around the vagina. EstroGel may also be used for purposes other than those listed here.