Please consult your physician before taking any medication. Generic Name: glipizide (GLIP ih zide) Brand Names: Glucotrol, Glucotrol XL What is glipizide? Glipizide is in a class of drugs called sulfonylureas. It is used to help control blood sugar levels. Glipizide is used to treat type 2 diabetes along with diet, exercise, and insulin therapy, if necessary. Glipizide may also be used for purposes other than those listed in this medication guide.