Please consult your physician before taking any medication. Generic Name: azithromycin (a zith row MY sin) Brand Names: Zithromax, Zithromax TRI-PAK, Zithromax Z-Pak, Zmax Azithromycin is in a group of drugs called macrolide antibiotics. Azithromycin fights bacteria in the body. Azithromycin is used to treat many different types of infections caused by bacteria, such as respiratory infections, skin infections, ear infections, and sexually transmitted diseases. Azithromycin may also be used for purposes other than those listed in this medication guide.